Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Wednesday, February 28, 2024

Smith wants same pharmacare deal as Quebec

Alberta premier Danielle Smith wants her province to have the same ability to opt out of the federal pharmacare plan, with full compensation, enjoyed by Quebec.

Smith says NDP, Liberals treating Albertans like second-class citizens with pharmacare | Western Standard | Jonathan Bradley:

February 27, 2024 - "Alberta Premier Danielle Smith blasted NDP leader Jagmeet Singh for saying Quebec can opt out of pharmacare and receive a larger health transfer payment, but Alberta could not. 'I’m tired of the NDP-Liberal coalition treating Albertans like second class citizens,' tweeted Smith on Tuesday. 'The same rules should apply equally across Canada'....

"Smith said Singh did not secure universal pharmacare. Rather, he secured a deal covering diabetes drugs and birth control. Alberta’s pharmacare plan sponsors more than 5,000 prescription drugs and provides coverage for many low-income people, seniors and people with disabilities.... 

"Alberta will take the additional healthcare dollars same as Quebec and invest it into improving our own provincial prescription drug program,' she said. 

"Smith said on Monday there might be a case for helping Albertans with the cost of prescription drugs. 

"An Alberta Health Services spokesperson said if any changes came from the Canadian government proposal, Alberta would opt out. The Alberta left wing said this decision was a tragedy."

Read more: https://www.westernstandard.news/alberta/smith-says-ndp-liberals-treating-albertans-like-second-class-citizens-with-pharmacare/52715

Sunday, June 19, 2022

Covid and the Medical-Industrial Complex

Covid Exposed the Medical-Pharmaceutical-Government Complex | Brownstone Institute - Mark Oshinskie:

Image: Salon, 2016.

June 18, 2022 - "In college, I took a Latin American Politics and Development class. When discussing Latin American medical care, Professor Eldon Kenworthy presented a deeply countercultural idea. Echoing a journal article by the scholar, Robert Ayres, Kenworthy maintained that building hospitals there costs lives. If, instead of erecting, equipping and staffing gleaming medical centers, this same money and human effort were devoted to providing clean water, good food and sanitation, the public health yield would be much greater. 

"United States medical history bears out Ayres’s paradox. The biggest increases in US life expectancy occurred early in the Twentieth Century, when people had increasing access to calories and protein, better water and sanitation. Lives lengthened sharply decades before vaccines, antibiotics or nearly any drugs were available, and a century before hospitals merged into corporate Systems. Incremental American life span increases during the past fifty years reflect far less smoking, safer cars and jobs, cleaner air and less lethal wars more than they reflect medical advances. Books like Ivan Illich’s Medical Nemesis and Daniel Callahan’s Taming the Beloved Beast echo Ayres’s critique. But PBS, CNN, B & N [Barnes & Noble], the NYT [New York Times], et al. censor such views.

"The American medical landscape has changed radically in the forty years since I learned of Ayres’ observation. America spends three times as much, as a percentage of GDP, on medical treatments as it did in the 1960s. By 2020, America devoted 18% of its GDP to medicine. (By comparison, about 5% goes to the military). Adding the mega-costs of mass testing and vaccines etc., medical expenditures might now approach 20%. Although the US spends more than twice per capita what any other nation spends on medical care, American ranks 46th in life expectancy. US life expectancy has flatlined, despite growing medical spending and broadened medical access via the vaunted Affordable Care Act. 

"Though medicine’s high-cost and relatively low yield are right in front of anyone who thinks about their medical experiences and those of people they know, most never connect the dots; more medical treatments and spending are continually advocated and applauded. There’s a regressive 'if it saves — or even slightly extends — one life' medical zeitgeist/ethic.

"As most medical insurance is employer-based, most people don’t notice annual premium increases. Nor do they see the growing slice of tax revenues used to subsidize Med/Pharma. Thus, they continually demand more stuff, like IVF, extremely high-cost drugs, sex changes or psychotherapy, as if these were their right, and free. To say nothing of these treatments’ limited effectiveness. As all are required to medically insure and to pay taxes, one can’t simply opt out or buy only those medical services that one thinks justify their costs. With massive, guaranteed funding sources, aggregate medical revenues will continue to climb. 

"Th[e] Medical-Industrial-Government Complex has become a Black Hole for today’s wealth. With great money comes great power. The Med/Pharma juggernaut rules the airwaves. Nonexistent until the 1990s, hospital System and drug ads now dominate advertising. By being such big advertisers, Med/Pharma dictates news content. Analysts who point out that lavish medical expenditures don’t yield commensurate public health benefit have small audiences. Med/Pharma critics can’t afford ads. 

"Medicine has fed Coronamania. The TV news I’ve seen during the past 27 months painted a very skewed picture of reality. The virus has been misrepresented — by the media and government, and by MDs, like Fauci, often posing in white jackets — as a runaway train that’s indiscriminately decimating the American populace. Instead of putting into perspective the virus’s clear demographic risk profile and the very favorable survival odds — even without treatment, at all ages, or promoting various forms of contra-Covid self-care, including weight loss — the media and medical establishment incited universal panic, and promoted counterproductive mass isolation, mass masking, mass testing, and treatment with ventilators and expensive, often harmful anti-virals. 

"Later, mass injections were added to the 'Covid-crushing' armamentarium. While the shots created many billionaires, and greatly enriched other Pfizer and Moderna stockholders, they failed, as Biden and many others had promised, to stop either infection or the spread. All of the many whom I know who have been infected in the past six months were vaxxed. 

"Many — whose voices are suppressed by mainstream media — [contend] that the shots have worsened outcomes, by driving the development of variants, weakening or confusing immune systems, and causing serious near-term injuries. Further, people blindly, ardently believed in the shots simply because they were marketed as 'vaccines' by bureaucrats wearing medical garb. Despite the shots’ failure and the failure of other 'mitigation' measures like lockdowns, masking and testing, many refuse to concede that Med/Pharma has had much — overwhelmingly negative — influence over the society and economy and public health during Coronamania. Nonetheless, many billions of dollars have been — and are still being — spent to advertise shots that most people don’t want. 

"The Covid overreaction has to some extent also piggy-backed on TV programs that have, for decades, glorified medicine in TV shows like Dr. Kildare, Marcus Welby, M.D., Medical Center, MASH, Gray’s Anatomy and House. Wearing white coats connotes virtue, just as did wearing white hats in Western movies. Given the cumulative PR onslaught of the ads and shows, medicine is widely seen as more effective than it is in real life....

"Medicine is the new American religion. Given such fervent belief in medicine’s importance and the sense of entitlement regarding expanding medical treatments, government and insurance money is relentlessly overallocated to medicine. Do these expenditures improve human outcomes? 

"During the first Scrubs episode, resident J.D. complains to his mentor that being a doctor was different than he had envisioned; most of his patients were 'old and kind of checked out.' His mentor responds, 'That’s Modern Medicine: advances that keep people alive who should have died a long time ago, back when they lost what made them human.' This largely describes those said to have died with Covid. Most people have disregarded that nearly all who died during the pandemic were old and/or in poor health. Most deaths have always occurred among the old and ill. Occasionally, sitcoms keep it realer than real people do.

"Aside from not helping much and misspending resources, and extending misery, medicine can be iatrogenic, i.e., it can cause illness or death. Hospital errors are said to cause from 250,000 to 400,000 American deaths annually. Perhaps medical personnel try to do a good job. but when the bodies of old, sick people are cut open or dosed with strong medicine, stuff happens. Even well-executed surgeries and many medications can worsen health. 

"Further, though few know it, a brew of excreted medications and diagnostic radionuclides daily pours down drains across the US and world and ends up in streams and rivers. For example, the hormones in widely-prescribed birth control pills feminize and disrupt aquatic creatures’ reproduction. There are books about all of this, too, though such authors never appear on Good Morning America

"Faith in medical interventions also lessens individual and institutional efforts to maintain or improve health. If people didn’t abuse substances, ate better and moved their bodies more, there would be much less demand for medical interventions. And if people spent less time working to pay for medical insurance, they could spend more time taking care of themselves and others. Overall, America could spend a fraction of what it spends on allopathic medicine and yet, be much healthier. There are also plenty of books about this. 

"Given its place at the center of American life for 27 months, and counting, Covid has been — and will be — used to further intensify the medicalization of individual lives, the economy, and society. By exploiting and building an irrational fear of death, the Medical Industrial Complex will promote the notion that we should double — or triple — down on medical and social interventions and investments that might marginally extend the lives of a small slice of the population. Or, in many instances, shorten lives. But most people who live sensibly are intrinsically healthy for many years. Given enough nutritious food, clean water and a decent place to sleep, most people will live a long time, with little or no medical treatment. While intensive medical interventions can marginally extend the lives of some old, sick people, medicine can’t reverse aging and it seldom restores vitality. 

"If the media were honest brokers, the Covid mania would never have taken hold. The media should have repeatedly pointed out that the virus only threatened a small, identifiable segment of a very large population. Instead, captive to its Med/Pharma sponsors, the media went full-frontal fearmonger and promoted intensive, society-wide intervention. Social, psychological and economic catastrophe ensued. Additionally, many doctors who could have spoken against the Covid craziness stayed silent so as not to jeopardize their licenses, hospital privileges or favored status with Pharma, or just because they were schooled in allopathic orthodoxy and hold fast to that faith. Props to those courageous few who broke ranks. 

"The Med/Pharma/Gov establishment, including the NIH and CDC, hasn’t saved America during 2020-22. To the contrary, Covid interventions have worsened overall societal outcomes. These net harms should have inflicted — and, depending on longer-term vaxx effects, may yet inflict — a big black eye on the Medical Industrial Complex." 

Read more: https://brownstone.org/articles/covid-exposed-the-medical-pharmaceutical-government-complex/

This work is licensed under a Creative Commons Attribution 4.0 International License.

Monday, April 4, 2022

Two repurposed drugs recognized to treat Covid

Two years into the Covid19 pandemic, Canadian provincial health authorities have begun repurposing inexpensive, widely available medicines for early outpatient treatment. Ontario is listing fluvoxamine, while Quebec is allowing the OTC sale of paxlovid to Covid-positive patients.

Ontario first in Canada to list fluvoxamine as COVID treatment | The Suburban - Joel Goldenberg:

December 23, 2021 - "Ontario is the first province in Canada to officially declare that the inexpensive anti-depressant fluvoxamine should be under consideration as a way to prevent people with mild cases of COVID-19 from having to be hospitalized. 

Ontario's Science Table says of fluvoxamine, '50 mg PO daily titrated up to 100 mg PO TID for 15 days may be considered for mildly ill patients presenting within seven days of symptom onset. This recommendation is based on very low certainty evidence of reduction in hospitalization, and the need for outpatient treatment options with a reasonable safety profile during an anticipated spike in COVID-19 cases due to the Omicron variant. Pharmacist consultation and outpatient provider follow-up is important to avoid any significant adverse drug interactions with fluvoxamine.'

"Fluvoxamine is sold in pharmacies as Luvox, and has been found in a study to cut COVID hospitalization significantly and can potentially reduce serious illness and deaths if prescribed early enough. As previously reported, the study was published in the medical journal Lancet Global Health, and took a look at results from 1,500 people in Brazil who were diagnosed early with COVID.... Those given fluvoxamine took it 100 mg twice a day for 10 days, and the result was that COVID hospitalization decreased by a third. As well, of those who took the medication, one died, compared to 12 who took the placebo.

"This past January, researchers at McGill University were also looking into fluvoxamine as a way to lessen COVID symptoms. Other universities have studied the drug as well, and it has been endorsed as a treatment by Johns Hopkins University."

Read more: https://www.thesuburban.com/news/city_news/ontario-first-in-canada-to-list-fluvoxamine-as-covid-treatment/article_56c1baa5-5d35-5740-84c0-8ab76ead8e29.html

Pharmacists can provide antiviral | The Suburban - Joel Ceasu:

April 1, 2022 - "Quebec pharmacists can now provide the antiviral Paxlovid ™ without a prescription to symptomatic patients who are at risk of developing complications and who present a positive screening test result for COVID-19.Access to a pharmacist from one of the 1,900 community pharmacies in Quebec will make it possible to offer residents local care and promote faster launch of treatment both for the individual and for the health care system.

"This can reduce the probability of hospitalization by up to 89% for vulnerable patients.... [I]nitiating treatment with Paxlovid ™ must be done within five days of the onset of symptoms. The drug was approved by Health Canada in January. Note that if, two days after the start of treatment, the patient's condition changes unfavorably, the pharmacist must refer them to a doctor or a specialized nurse practitioner. 'It is essential that people who have a condition potentially relevant to the use of Paxlovid TM make sure to quickly undergo a screening test for COVID-19 as soon as the first symptoms appear' reads a Health ministry statement. 'If the result is positive, they should promptly consult a pharmacist, a doctor or a specialized nurse practitioner.'

"If other COVID-19 treatments become available and recommended by the National Institute of Excellence in Health and Social Services (INESSS), pharmacists may also prescribe them. The drug will be available following the positive test or with a prescription from a doctor or a nurse practitioner." 

Read more: https://www.thesuburban.com/news/city_news/pharmacists-can-provide-antiviral/article_15c5a917-7126-571e-ab2f-52fd412c4881.html#tncms-source=block-contextual-fallback 

Sunday, March 27, 2022

Israeli data shows vitamin D efficacy vs Covid

Israeli study offers strongest proof yet of vitamin D’s power to fight COVID | Times of Israel - Nathan Jaffay:

3 February 3, 2022 - "Israel scientists say they have gathered the most convincing evidence to date that increased vitamin D levels can help COVID-19 patients reduce the risk of serious illness or death. Researchers from Bar Ilan University and the Galilee Medical Center say that the vitamin has such a strong impact on disease severity that they can predict how people would fare if infected based on nothing more than their ages and vitamin D levels.

"Lacking vitamin D significantly increases danger levels, they concluded in newly peer-reviewed research published Thursday in the journal PLOS One. The study is based on research conducted during Israel’s first two waves of the virus, before vaccines were widely available, and doctors emphasized that vitamin supplements were not a substitute for vaccines, but rather a way to keep immunity levels from falling.

"Vitamin D deficiency is endemic across the Middle East, including in Israel, where nearly four in five people are low on the vitamin, according to one study from 2011. By taking supplements before infection, though, the researchers in the new Israeli study found that patients could avoid the worst effects of the disease.

"'We found it remarkable, and striking, to see the difference in the chances of becoming a severe patient when you are lacking in vitamin D compared to when you’re not,' said Dr. Amiel Dror, a Galilee Medical Center physician and Bar Ilan researcher who was part of the team behind the study. He noted that his study was conducted pre-Omicron, but said that the coronavirus doesn’t change fundamentally enough between variants to negate vitamin D effectiveness. 'What we’re seeing when vitamin D helps people with COVID infections is a result of its effectiveness in bolstering the immune systems to deal with viral pathogens that attack the respiratory system,' he told The Times of Israel. 'This is equally relevant for Omicron as it was for previous variants.'

"Health authorities in Israel and several other countries have recommended vitamin D supplements in response to the coronavirus pandemic, though data on its effectiveness has been sparse until now. In June, researchers published preliminary findings showing that 26 percent of coronavirus patients died if they were vitamin D deficient soon before hospitalization, compared to 3% who had normal levels of vitamin D. They also determined that hospitalized patients who were vitamin D deficient were 14 times more likely, on average, to end up in severe or critical condition than others. 

"While the scientific community recognized the importance of the results, questions arose as to whether recent health conditions among the patients might have been skewing the results. The possibility was raised that patients could have been suffering from conditions that both reduce vitamin D levels and increase vulnerability to serious illness from COVID-19, meaning the vitamin deficiency would be a symptom rather than a contributing factor in disease severity.

"To zero out that possibility, Dror’s team delved deeper into the data, examining each of its patients’ vitamin D levels over the two-year stretch before coronavirus infection. They found that the strong correlation between sufficient vitamin D levels and ability to fight the coronavirus still held, and the level of increased danger in their preliminary findings remained almost identical....

"A flood of dubious claims about natural remedies to the coronavirus, including a theory that Israelis had immunized themselves with lemons and baking soda, have left some skeptical about claims of vitamins warding off the virus. But Dror insisted that his team’s research showed that the importance of vitamin D was not based on incomplete or flawed data. 'People should learn from this that studies pointing to the importance of taking vitamin D are very reliable, and aren’t based on skewed data,' he said. 'And it emphasizes the value of everyone taking a vitamin D supplement during the pandemic, which, consumed in sensible amounts in accordance with official advice, doesn’t have any downside.'"

Read more: https://www.timesofisrael.com/israeli-study-offers-strongest-proof-yet-of-vitamin-ds-power-to-fight-covid/ 

Read study: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263069

Sunday, November 21, 2021

Antidepressant cuts Covid ICU cases and deaths

Common antidepressant slashes risk of COVID death, study says | Nature - Saima May Sidik:

October 29, 2021 - "A cheap, widely available drug used to treat mental illness cuts both the risk of death from COVID-19 and the need for people with the disease to receive intensive medical care, according to clinical-trial results. The drug, called fluvoxamine, is taken for conditions including depression and obsessive–compulsive disorder. But it is also known to dampen immune responses and temper tissue damage, and researchers credit these properties with its success in the recent trial. Among study participants who took the drug as directed and did so in the early stages of the disease, COVID-19-related deaths fell by roughly 90% and the need for intensive COVID-19-related medical care fell by roughly 65%.

"'A major victory for drug repurposing!' Vikas Sukhatme at Emory University School of Medicine in Atlanta, Georgia, who studies drug repurposing, wrote in an e-mail to Nature. 'Fluvoxamine treatment should be adopted for those at high risk for deterioration who are not vaccinated or cannot receive monoclonal antibodies.'

"Study co-author Angela Reiersen, a psychiatrist at Washington University School of Medicine in St Louis, Missouri, [who] has long been interested in using fluvoxamine to treat a rare genetic condition ... came across a 2019 study showing that fluvoxamine reduced inflammation in mice with sepsis. When COVID-19 hit, 'I immediately thought back to that paper with the mice,' she says. Reiersen and her colleagues partnered with the organizers of the TOGETHER Trial, which aims to identify approved drugs that can be repurposed to treat COVID-19. The team’s study included 1,497 people in Brazil who had COVID-19 and were at high risk of severe disease. Roughly half received fluvoxamine, and the rest received a placebo.

"The trial’s results, published on 27 October, mean that fluvoxamine is one of a handful of therapies that show strong evidence of preventing progression from mild to severe COVID-19. The only early-stage treatments currently recommended by the US National Institutes of Health are monoclonal antibodies, which are costly and difficult to administer in an outpatient setting. Experts are excited about the results, but stress that there are caveats.... 

"Fluvoxamine’s low cost could make it accessible worldwide, says study co-author Edward Mills, a health researcher at McMaster University in Hamilton, Canada. A ten-day course costs only about US$4, and the drug’s patents have expired, meaning that any company can produce it.... It’s possible that pairing fluvoxamine with a drug that interferes with viral replication, such as Merck’s upcoming antiviral molnupiravir, could be even more effective, Mills says."

Read more: https://doi.org/10.1038/d41586-021-02988-4

Read study: https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00448-4/fulltext

Friday, November 5, 2021

Blood thinners cut Covid deaths almost in half

Blood thinners can reduce COVID-19 deaths by nearly half, study finds | CTV News - Anthony Vasquez-Peddie:

October 3, 2021 - "The use of blood thinners by COVID-19 patients, either before being infected with the disease or afterward, can reduce deaths by almost half, according to new research. The study, published in the open-access, peer-reviewed journal EClinicalMedicine, looked at ways to reduce clotting and hospitalizations related to COVID-19 through the use of prescribed blood thinners.

"'We know that COVID-19 causes blood clots that can kill patients,' Dr. Sameh Hozayen, lead author of the study and an assistant professor of medicine at the University of Minnesota Medical School, said in a news release.... 'Blood thinners are medications prescribed to prevent blood clots in patients with a prior blood clot in their lungs or legs. They also prevent blood clots in the brain secondary to abnormal heart rhythms, like atrial fibrillation. Blood thinners are the standard of treatment in these diseases, which is why we looked at data to see if it impacted hospitalizations related to COVID-19'.... 

"The study also found that patients on blood thinners before contracting the virus were admitted less often to hospital despite being older on average and suffering from more chronic medical conditions than their peers.

"The study evaluated 6,195 adult COVID-19 patients, including 598 who were immediately hospitalized and 5,597 who were treated as outpatients, between March 4 and Aug. 28, 2020. Among the outpatients, 160 were already on blood thinners, and 331 were eventually hospitalized. Outpatients who were on blood thinners at the time of diagnosis had a 43 per cent reduced risk of hospitalization. Hospitalized patients also benefitted from blood thinners regardless of the type or dose of medication used.

"Most medical centres around the world currently have protocols for starting COVID-19 patients on blood thinners upon hospital admission, according to Dr. Hozayen. It’s easy to keep track of prescription drug use while in hospital, but among those who have previously been prescribed blood thinners and may want to benefit from this study, one of the challenges is getting them to adhere to their drug regimen.

"'Unfortunately, about half of patients who are being prescribed blood thinners for blood clots in their legs, lungs, abnormal heart rhythms or other reasons do not take them. By increasing adherence for people already prescribed blood thinners, we can potentially reduce the bad effects of COVID-19,' he said. 'Outside of COVID-19, the use of blood thinners is proven to be lifesaving for those with blood coagulations conditions.'"

Read more: https://www.ctvnews.ca/health/coronavirus/blood-thinners-can-reduce-covid-19-deaths-by-nearly-half-study-finds-1.5609242 

Read study: https://www.sciencedirect.com/science/article/pii/S2589537021004193

Sunday, September 12, 2021

How the Covid pandemic is changing science

How the Pandemic Is Changing the Norms of Science | Tablet - John P.A. Ioannidis: 

September 8, 2021 - "The crisis caused by the lethal COVID-19 pandemic and by the responses to the crisis have made billions of people worldwide acutely interested and overexcited about science. Decisions pronounced in the name of science have become arbitrators of life, death, and fundamental freedoms. Everything that mattered was affected by science.... One problem with this new mass engagement with science is that most people, including most people in the West, had never been seriously exposed to the fundamental norms of the scientific method. The Mertonian norms of communalism, universalism, disinterestedness, and organized skepticism have unfortunately never been mainstream in education, media, or even in science museums and TV documentaries on scientific topics....

"Indeed, change did happen — but perhaps mostly for the worst.... Lack of communalism during the pandemic fueled scandals and conspiracy theories, which were then treated as fact in the name of science by much of the popular press and on social media. The retraction of a highly visible hydroxychloroquine paper from The Lancet was a startling example: A lack of sharing and openness allowed a top medical journal to publish an article in which 671 hospitals allegedly contributed data that did not exist, and no one noticed this outright fabrication before publication.... 

"The pandemic led seemingly overnight to a scary new form of scientific universalism. Everyone did COVID-19 science or commented on it. By August 2021, 330,000 scientific papers were published on COVID-19, involving roughly a million different authors. An analysis showed that scientists from every single one of the 174 disciplines that comprise what we know as science has published on COVID-19....  At first sight, this was an unprecedented mobilization of interdisciplinary talent. However, most of this work was of low quality, often wrong, and sometimes highly misleading. Many people without subject-matter technical expertise became experts overnight, emphatically saving the world.... Many amazing scientists have worked on COVID-19. I admire their work.... However, alongside thousands of solid scientists came freshly minted experts with questionable, irrelevant, or nonexistent credentials and questionable, irrelevant, or nonexistent data.

"Social and mainstream media have helped to manufacture this new breed of experts. Anyone who was not an epidemiologist or health policy specialist could suddenly be cited as an epidemiologist or health policy specialist by reporters who often knew little about those fields but knew immediately which opinions were true. Conversely, some of the best epidemiologists and health policy specialists in America were smeared as clueless and dangerous by people who believed themselves fit to summarily arbitrate differences of scientific opinion without understanding the methodology or data at issue.

"Disinterestedness suffered gravely.... During the pandemic, ... conflicted entities were raised to the status of heroes. For example, Big Pharma companies.... Other potentially conflicted entities became the new societal regulators.... Big Tech companies, which gained trillions of dollars in cumulative market value from the virtual transformation of human life during lockdown, developed powerful censorship machineries that skewed the information available to users on their platforms. Consultants who made millions of dollars from corporate and government consultation were given prestigious positions, power, and public praise, while unconflicted scientists who worked pro bono but dared to question dominant narratives were smeared as being conflicted. 

"Organized skepticism was seen as a threat to public health. There was a clash between two schools of thought, authoritarian public health versus science — and science lost.... Honest, continuous questioning and exploration of alternative paths are indispensable for good science. In the authoritarian ... version of public health, these activities were seen as treason and desertion. The dominant narrative became that 'we are at war.' When at war, everyone has to follow orders. If a platoon is ordered to go right and some soldiers explore maneuvering to the left, they are shot as deserters. Scientific skepticism had to be shot, no questions asked. The orders were clear....

"This is a dirty war, one without dignity. Opponents were threatened, abused, and bullied by cancel culture campaigns in social media, hit stories in mainstream media, and bestsellers written by zealots. Statements were distorted, turned into straw men, and ridiculed. Wikipedia pages were vandalized. Reputations were systematically devastated and destroyed. Many brilliant scientists were abused and received threats during the pandemic, intended to make them and their families miserable." 

Read more: https://www.tabletmag.com/sections/science/articles/pandemic-science

Monday, September 6, 2021

Misinformation about ivermectin

by George J. Dance

As readers know, the blog is interested in possible treatments for Covid19. I do not think, like some, that vaccines make those unnecessary; even if it were true (which it is not) that vaccines provided complete protection against catching covid, they would still be useless for those who have already caught it. Plenty of people are still catching it these days, many of whom had no access to a vaccine anyway (either because it was not available, or due to government restrictions). So Covid medicines and treatments should concern us. 

One of the medicines I have blogged about is ivermectin (IVM); some of those stories have been encouraging, but the truth is still out there. We are a long way from having all the data we need on the drug's efficacy, or possibly (despite its 40 years of approved use as a human medicine) even on its safety. That is why this weekend's news from Oklahoma was so alarming. I have seen plenty of stories about ivermectin poisoning before, but those usually concluded, like this recent report from Mississippi, that "No one has been hospitalized" from ingesting it. The news out of Oklahoma was different.    

According to the story, first reported on KFOR-TV (video below), eastern Oklahoma was seeing an epidemic of people being hospitalized for overdosing on IVM. So many were being hospitalized, in fact, that local hospitals were overwhelmed and on the verge of collapse. That story was picked up by, among others, BBC News, yahoo newsNewsweek, the New York Daily NewsThe Guardian, The IndependentMSN.com, and even Rolling Stone magazine. As the last reported, under the title "Gunshot Victims Left Waiting as Horse Dewormer Overdoses Overwhelm Oklahoma Hospitals, Doctor Says":  

The rise in people using ivermectin, an anti-parasitic drug usually reserved for deworming horses or livestock, as a treatment or preventative for Covid-19 has emergency rooms “so backed up that gunshot victims were having hard times getting” access to health facilities, an emergency room doctor in Oklahoma said.

This week, Dr. Jason McElyea told KFOR the overdoses are causing backlogs in rural hospitals, leaving both beds and ambulance services scarce.

“The ERs are so backed up that gunshot victims were having hard times getting to facilities where they can get definitive care and be treated,” McElyea said.

“All of their ambulances are stuck at the hospital waiting for a bed to open so they can take the patient in and they don’t have any, that’s it,” said McElyea. “If there’s no ambulance to take the call, there’s no ambulance to come to the call.”

The doctor added that IVM OD victims "have arrived at hospitals with negative reactions like nausea, vomiting, muscle aches, and cramping — or even loss of sight. 'The scariest one that I’ve heard of and seen is people coming in with vision loss,' the doctor said."

The one thing that amazed me was that there was no attempt to corroborate Dr. McElyea's report, or to factcheck it either; it was reported as a factual account requiring no independent support. Rolling Stone did cite a story in Tulsa World, which reported that  "a rural emergency room physician, had a gunshot victim in his facility whom for hours he was unable to transfer to a higher level of care because no one had space." However, (1) the gist of that article was that a surge in patients suffering from Covid (not IVM overdoses, which were not mentioned) was causing the problem; and (2) the physician in question turned out to be Dr. McElyea himself.  

Not one of the media outlets running the story bothered to pick up a telephone, or get onto the internet, and check with a single Oklahoma hospital. Only one source, BBC News, bothered even to speak with Dr. McElyea to verify his quotes. What McElyea told the BBC, though, was only that "a 'handful' of people overdosing on [IVM] were putting further strain on hospital staff already stretched by a surge in Covid cases." Oklahoma hospitals were being overwhelmed, but by Covid cases, not by "horse dewormer overdoses."

After reading the BBC story, I began thinking that McElyea's original remarks had been either misunderstood, or misrepresented for the sake of a better story, by the KFOR reporter, Katelynn Ogle. Meanswhile, over at Reason magazine, Robby Soave had reached a similar conclusion:

One might be tempted to blame McElyea for embellishing his story.... But a closer look at the KFOR story reveals something quite startling: At no point did McElyea actually come out and say that ivermectin overdoses were straining hospitals.... McElyea clearly states that ivermectin overdoses have been a problem, and he claims that some hospitals are dealing with strain. But he never actually connects these two issues. It was the journalist, Ogle, who added that framing. She did not respond to a request for comment.

Eventually a statement was issued by an Oklahoma hospital where Dr. McElyea has worked. There turned out to a few discrepancies between their account and the TV station's: 

Although Dr. Jason McElyea is not an employee of NHS Sequoyah, he is affiliated with a medical staffing group that provides coverage for our emergency room. With that said, Dr. McElyea has not worked at our Sallisaw location in over 2 months. NHS Sequoyah has not treated any patients due to complications related to taking ivermectin. This includes not treating any patients for ivermectin overdose. All patients who have visited our emergency room have received medical attention as appropriate. Our hospital has not had to turn away any patients seeking emergency care. 

Once again, no hospitalizations due to use of IVM. But that was not the end of the story. A day later, a second hospital had issued its own statement, which confirmed Dr. McElyea's claims about IVM overdoses. However, the same statement also noted that the doctor had repudiated the KFOR story: 

Jason McElyea, D.O. ... has privileges at INTEGRIS Grove Hospital. He also works in several other emergency departments in rural Oklahoma. There is a lot of media attention surrounding remarks reportedly made by Dr. McElyea. While we do not speak on his behalf, he has publicly said his comments were misconstrued and taken out of context. What we can confirm is that we have seen a handful of ivermectin patients in our emergency rooms.... And ... while our hospitals are not filled with people who have taken ivermectin, such patients are adding to the congestion already caused by COVID-19 and other emergencies. 

That looks like the end of the story. Dr. McElyea had told KFOR-TV about this "handful" of IVM overdoses (the same word the BBC quoted him as using), some of which might have led to hospitalization (though the hospital does not confirm that any did). KFOR-TV selectively used the good doctor's recorded comments to construct a piece of fake news, and thereby spread misinformation.  

Updated, September 8, 2021


One more thing needs to be said on the subject. While the above story was pure misinformation, there was a real problem throughout the summer, not just in Oklahoma, with some people eating horse dewormer paste, and other livestock medications containing IVM, and accidentally overdosing. The U.S. Food and Drug Administration (FDA) found it necessary to issue an advisory warning:

Never use medications intended for animals on yourself or other people. Animal ivermectin products are very different from those approved for humans. Use of animal ivermectin for the prevention or treatment of COVID-19 in humans is dangerous.... animal drugs are often highly concentrated because they are used for large animals like horses and cows, which weigh a lot more than we do — a ton or more. Such high doses can be highly toxic in humans. Moreover, the FDA reviews drugs not just for safety and effectiveness of the active ingredients, but also for the inactive ingredients. Many inactive ingredients found in  products for animals aren’t evaluated for use in people.

While the FDA considers both human- and animal-formulated IVM to be ineffective, it calls only "Use of animal ivermectin for the prevention or treatment of COVID-19 in humans" dangerous. IVM for humans is formulated in a dosage safe for humans, and uses only ingredients that the FDA has approved for use in humans. So why were so many people taking animal-formulated products like horse dewormer paste instead? 

The answer is simple: The FDA has approved the over-the-counter (OTC) sale of horse dewormer paste; but it has not allowed the OTC sale of IVM formulated for humans. To get the latter, those wishing to try the medicine need a doctor's prescription, which creates a high (in some cases impassable) barrier to access. If Americans could buy ivermectin for humans OTC, there would have been no reason for them to eat horse dewormer paste instead. That the horse dewormer epidemic happened at all was solely due to the FDA's own regulations; any increased danger to Americans caused by it was danger caused by the FDA itself. 

(It is theoretically possible to overdose on human-formulated IVM. However, the chance of that is extremely improbable; not only is the dosage fully controlled, but the labelling and the pharmacist are both available to instruct users on how to safely use it.)  

In the above video, Dr. McElyea says: "There’s a reason you have to have a doctor to get a prescription for this stuff because it can be dangerous.' However, in this case it looks like the doctor reversed causation. Ivermectin was only dangerous, in this instance, because Americans were taking an unsafe formulation; and they were taking an unsafe formulation because without a doctor's approval they could not take a safe one. 

Updated December 8, 2021

Wednesday, July 28, 2021

The story behind the Long Covid story

The Dubious Origins of Long Covid | Wall Street Journal - Jeremy Devine:

March 22, 2021 - "‘Long Covid,” or post-Covid syndrome, is an emerging condition that has attracted great media attention — and now [U.S.] federal funding. The National Institutes of Health [NIH] last month announced a $1.15 billion initiative to research the 'prolonged health consequences' of Covid-19 infection. The topic deserves serious study. Some patients, particularly older ones with co-morbidities, do experience symptoms that outlast a coronavirus infection. But such symptoms can also be psychologically generated or caused by a physical illness unrelated to the prior infection. Long Covid is largely an invention of vocal patient activist groups....

"The concept of long Covid has a highly unorthodox origin: online surveys produced by Body Politic, which launched in 2018 and describes itself atop its website’s homepage as 'a queer feminist wellness collective merging the personal and the political.' In March 2020, the group’s co-founders created the Body Politic Covid-19 Support Group, and as part of their mission of 'cultivating patient led research,' the organization coordinated a series of online surveys on persistent symptoms. Based on the results of these, Body Politic produced the first report on long Covid in May.

"But many of the survey respondents who attributed their symptoms to the aftermath of a Covid-19 infection likely never had the virus in the first place. Of those who self-identified as having persistent symptoms attributed to Covid and responded to the first survey, not even a quarter had tested positive for the virus. Nearly half (47.8%) never had testing and 27.5% tested negative for Covid-19. Body Politic publicized the results of a larger, second survey in December 2020. Of the 3,762 respondents, a mere 600, or 15.9%, had tested positive for the virus at any time....

"This didn’t perturb NIH Director Dr. Francis Collins, who has repeatedly supported the Body Politic Covid-19 Support Group’s patient-led research initiatives, promoting the surveys in a series of official blog posts. In the announcement of the NIH’s decision to commit $1.15 billion to long Covid research, Dr. Collins explicitly referred to the Body Politic research surveys.

This subjugation of scientific rigor to preconceived belief reflects a common dynamic encountered in clinical practice. Patients who struggle with chronic and vague symptoms often vehemently reject a physician’s diagnosis that suggests an underlying mental-health issue, in part because of the stigma around mental illness and the false belief that psychologically generated symptoms aren’t 'real.' By relinquishing the need for objective serological confirmation, and by claiming that long Covid can manifest in a mind-boggling 205 different symptoms, the Body Politic Covid-19 Support Group offered its readership exactly this attractive alternative, leading patients away from treatments that could actually ease their symptoms.

"Body Politic wasn’t the only patient advocacy group that drove the NIH funding commitment. Solve ME/CFS (which stands for myalgic encephalomyelitis/chronic fatigue syndrome) was founded in 1987 by patients who felt their chronic and numerous medical complaints — including fatigue, “brain fog,” and an inability to exert themselves physically or mentally — were being dismissed by their physicians and neglected by the medical community.... In 2017, frustrated by the lack of mainstream recognition of their condition, Solve ME/CFS hired a lobbyist to pressure federal agencies to commit more funds to research. Then, in December 2020, likely sensing an intuitive link with the emerging idea of long Covid syndrome, this same organization spearheaded a letter — also signed by Body Politic — to congressional leaders urging more federal funding be dedicated to investigating long Covid....

"A central feature underlying many psychosomatic-symptom disorders is a fixed belief that one is ill and unlikely to recover. By drawing attention to and legitimizing the ever-present threat of long Covid, medical authorities will lead a large group of impressionable patients to believe that their Covid-19 symptoms have not resolved and that they are helpless victims of an unrelenting sickness. 

"In the past century, the media has played a critical role in perpetuating psychogenic illnesses —  chronic brucellosis in the 1940s, chronic Epstein Barr virus in the 1980s, and today (although scientifically debunked) chronic Lyme disease. It is therefore alarming to witness the recent proliferation of uncritical and sensational media stories about long Covid. The NIH’s decision is a victory for pseudoscience and will do more to harm than help patients."

Read more: https://www.wsj.com/articles/the-dubious-origins-of-long-covid-11616452583

Dr. Devine is a resident psychiatrist at McMaster University in Hamilton, Ontario.

Friday, July 16, 2021

Ivermectin reduces severity of Covid infection, Pasteur Institute finds

Ivermectin reduces 'the severity of infection' with Covid-19, according to the Pasteur Institute - RT France (Google translated):

July 14, 2020 - "The Pasteur Institute is fueling the debate on ivermectin. The research center unveiled on July 12 a study on the effects of this antiparasitic treatment against Covid-19, which concludes that 'taking this drug at standard doses makes it possible to reduce in an animal model the symptoms and the severity of SARS-CoV-2 infection'. The work of the scientists of the institute, published in the journal of the European Organization of Molecular Biology, thus underline that the ivermectin molecule causes 'a limitation of the inflammation of the respiratory tract and the symptoms which result from it' and 'protection against loss of smell'. 

"[T]he treatment does not seem to act on viral replication: 'The treated and untreated models had similar amounts of viral load in the nasal cavity and in the lungs. Our results show that ivermectin has an immunomodulatory and not an antiviral effect,' explained Guilherme Dias de Melo, epidemiologist and co-author of the study. Hervé Bourhy, head of unit at the Institut Pasteur who also took part in the work, nevertheless believes that these 'results provide significant progress and [...] pave the way for development axes for better treatments against Covid -19 in humans'. 

"Ivermectin is an antiparasitic commonly used against parasites such as scabies, onchocerciasis (river blindness) or lice. The drug is the subject of a promotional campaign on the networks, in particular since an Australian study published in the spring of 2020 had observed an in vitro efficacy of the ivermectin molecule on Sars-CoV-2

"But on March 31, a WHO [World Health Organization] clinical team said that the data from studies to measure their effectiveness against Covid-19 had not provided convincing results.... In addition, the manufacturer of the drug, Merck, assured on February 4 that the idea of ​​a 'potential therapeutic effect against Covid-19 has no scientific basis'.... 

"'Most often carried out in emerging countries, these clinical trials did not meet the conditions required for the testing of drugs in our country. This has led to criticism both within the World Health Organization and within the Directorate-General for Health' explained ... Jean-Pierre Changeux, famous neurobiologist co-signatory of the French study. Another factor, 'the controversy around hydroxychloroquine [another antiparasitic] has greatly affected the objective evaluation of ivermectin', argued the researcher. 

"[T]he institute's team followed a path developed over the past year by Jean-Pierre Changeux with Zahir Amoura, from Pitié-Salpêtrière. In March 2020, one of the latter's interns wondered about Chinese studies showing a low number of smokers among the sick. They then worked on the protection potential of nicotine against Covid-19. The two scientists started from the idea that the virus enters the body through the nicotinic receptor, a protein contained in neurons that Jean-Pierre Changeux himself had discovered and isolated in 1970. 'Our hypothesis is that the coronavirus would block directly or indirectly this receptor and that ivermectin could reactivate it' explained the neurobiologist.... 

"Despite the disavowal of the WHO, the drug has already met with success in several countries such as Brazil, Lebanon and South Africa. In Indonesia, AFP reports that pharmacies are facing a rush on ivermectin. Also in India, where a collective of lawyers from Bombay has announced that it is launching a lawsuit against Soumya Swaminathan, a pediatrician specializing in tuberculosis and scientific director of the WHO. Indian lawyers accuse him of dismissing evidence in favor of ivermectin, of having tweeted advising against its use (which they liken to disinformation leading to deaths), and of promoting laboratories that produce vaccines."

Read more: https://francais.rt.com/france/88707-ivermectine-reduit-gravite-infection-covid-19-selon-institut-pasteur

Read study: https://www.pasteur.fr/fr/espace-presse/documents-presse/ivermectine-attenue-symptomes-covid-19-modele-animal

Tuesday, June 22, 2021

Ivermectin cuts Covid deaths, review study shows


June 21, 2021 - "Use of the anti-parasitic drug ivermectin could reduce COVID-19-related deaths, data from a peer-reviewed study shows. The study, published last week in the American Journal of Therapeutics, analyzed data from multiple clinical studies assessing ivermectin as a potential treatment for COVID-19. Ivermectin, which is approved by the U.S. Food and Drug Administration (FDA) as a treatment for intestinal strongyloidiasis and onchocerciasis, which are two conditions caused by parasitic worms, has anti-inflammatory properties....

"First reported by The Epoch Times, the data showed ivermectin reduced the risk of death in mild-to-moderate patients by an average of 62%. The study data further suggests that risk of death was found to be 2.3% among hospitalized patients treated with ivermectin, compared to 7.8% for those who were not. The team did note that there may be no benefit for patients who are in need of mechanical ventilation.

"'Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally,' the study authors concluded.

"As BioSpace has previously reported, researchers in Australia showed in a laboratory setting that treatment with ivermectin inhibited the COVID-19 virus within 24 to 48 hours of treatment. The preclinical data showed that ivermectin prevented the virus’ RNA from replicating. That particular test showed that ivermectin targets the SARS-CoV-2 virus like a parasite.

"The latest assessment of those multiple studies seems to confirm the potential of ivermectin against COVID-19. However, the FDA currently maintains a web page warning against the unauthorized use of ivermectin to treat the virus. The FDA said it has received multiple reports of patients who have required medical support and been hospitalized after self-medicating with ivermectin that had been approved for use as an anti-parasitic drug in animals.... The FDA notes that clinical studies are underway assessing ivermectin against COVID-19, but until those are reviewed and confirmed, it will warn against taking unauthorized medication."


Thursday, May 20, 2021

First homegrown Covid drug approved in India

Why All Eyes Are On 2-DG, The New Drug That India's Launched Against Covid-19 | News 18 India - Kenneth Mohanty:

May 20, 2021 - " A surge in serious cases during the devastating second wave of Covid-19 in India has been accompanied by desperate efforts ... to seek out every last lead on promising treatments and medications that can save the lives of their loved ones. Amid the despair and confusion comes 2-DG, the indigenously developed Covid-19 drug launched in collaboration with a defence lab....

"2-DG, short for 2-deoxy-D-Glucose, was developed by the Institute of Nuclear Medicine and Allied Sciences (INMAS) — a lab that is part of the Defence Research and Development Organisation (DRDO) — in collaboration with Dr. Reddy’s Laboratories, Hyderabad. The drug is a result of laboratory experiments launched in April 2020 that found this molecule was effective against SARS-CoV-2 virus and inhibited viral growth. 2-DG comes in powder form in a sachet and is to be taken orally after dissolving it in water.

"The Drugs Controller General of India (DCGI), which is the national drug regulator, approved its emergency use on May 1, the Ministry of Defence said earlier this month. Defence Minister Rajnath Singh and Health Minister Dr Harsh Vardhan released the first batch of the drug on May 17. According to the defence ministry, clinical trials have shown that the drug helps in faster recovery of hospitalised patients and reduces supplemental oxygen dependence.

"It works by accumulating in the virus-infected cells of patients and prevents virus growth by stopping viral synthesis and energy production. The ministry said that 'its selective accumulation in virally infected cells makes this drug unique'. It added that a higher proportion of patients treated with 2-DG were found to display 'RT-PCR negative conversion' and that the 'drug will be of immense benefit' to Covid-19 patients.... It is to be used as an adjunct therapy, which means it can supplement the primary line of treatment for such patients....

"Dr Reddy’s Laboratories said on May 19 that commercial launch of 2-DG and its supply to government and private hospitals will begin some time in mid-June. It added that the price per sachet will be fixed with a view to making it affordable for as many patients as possible and warned against attempts to pass off fake and illegal products as the 2-DG drug. The defence ministry had said that 2-DG is derived from a generic molecule that is an analogue of glucose and, hence, 'can be easily produced and made available in plenty in the country'.

"Phase-II trials conducted on 110 patients between May and October, 2020 showed that the drug was safe and led to significant improvement in the recovery of Covid-19 patients. The defence ministry said that patients administered 2-DG 'showed faster symptomatic cure than Standard of Care (SoC) on various endpoints' and that there was a median difference of 2.5 days in achieving normalisation of specific parameters as compared with the standard care protocol.

"The Phase-III clinical trial, which was held for 220 patients between December last year and March 2021, reported that a significantly higher proportion of patients (42% vs 31%) improved and could be taken off supplemental oxygen by Day 3 compared with those who received standard care. A similar trend was seen in 65+ year patients....

"While 2-DG has been explored in cancer therapy, its use for Covid-19 treatment needs to be studied further, The Indian Express cited experts as saying. Doctors have also pointed to the small sample sizes of 2-DG’s clinical trials while suggesting that more data should be awaited before the drug can be confidently said to check the course of Covid-19 infection in patients."

Read more: https://www.news18.com/news/india/why-all-eyes-are-on-2-dg-the-new-drug-that-indias-launched-against-covid-19-3757100.html

Thursday, April 29, 2021

Covid antibody treatment going unused in Canada

Canadian-made COVID-19 antibody treatment sitting on shelves due to lack of administration plan | CTV News - Avis Favaro, Elizabeth St. Philip, Brooklyn Neustaeter, Solarina Ho:

April 24, 2021 - "A Canadian-made COVID-19 antibody treatment is sitting on hospital and pharmacy shelves amid the country’s third wave of the pandemic because doctors say a plan on how to administer the drug was never made.... 

"Bamlanivimab is a monoclonal antibody directed against the spike protein of SARS-CoV-2, the virus that causes COVID-19. The drug mimics the immune system’s ability to fight off the virus and was developed by AbCellera Biologics Inc. in Vancouver with the support of the federal government, which had committed up to $175.6 million to the company in May 2020 to develop antibody therapies.... The one-dose treatment, which is sold by Eli Lilly Canada, Inc., can be used in health-care facilities such as hospitals, as it is given by infusion into the veins of patients. As an antibody therapy, it is part of a major class of drugs normally used to treat diseases like cancer and rheumatoid arthritis, Sachdev Sidhu, a professor of molecular genetics at the University of Toronto, said in an interview....

"Health Canada authorized the drug in November 2020 under the interim order respecting the importation, sale and advertising of drugs for use in relation to COVID-19. According to Health Canada, 26,000 doses of the treatment were purchased for $40 million and distributed amongst the provinces. However, almost none of those doses have been used.

"Countries around the world have been using bamlanivimab to help keep COVID-19 patients out of hospital and reduce deaths for months. More than 400,000 COVID-19 patients worldwide have benefited from the drug, according to Michael McDougall, a spokesperson for Eli Lilly.... According to AbCellera Biologics, studies have shown the treatment is effective against SARS-CoV-2, and the variant first identified in the United Kingdom. Despite this, provincial health authorities have not yet made the treatment available to Canadians.

"AbCellera Biologics CEO Carl Hansen told CTV National News ... that provincial government[s] did not issue a plan on how to administer the treatment, causing doctors to leave it on shelves.... CTV News has reached out to provincial health units for comment, but did not hear back before this story was published....

"[T]he U.S. Food and Drug Administration’s recent revocation of bamlanivimab’s Emergency Use authorization could cause some confusion with the public. A Health Canada spokesperson told CTVNews.ca via email that ... 'There is no change to bamlanivimab authorization in Canada and Eli Lilly has not requested that Health Canada revoke its authorization. Bamlanivimab used by itself is effective against the B.1.1.7 (UK) variant, which is the main variant circulating in Canada at this time.'" 

Read more: https://www.ctvnews.ca/health/coronavirus/canadian-made-covid-19-antibody-treatment-sitting-on-shelves-due-to-lack-of-administration-plan-1.5396804

Friday, April 23, 2021

NY patients win court battles to use ivermectin

Ivermectin Wins in Court Again: For Human Rights | Deseret News - Justus R. Hope, MD:

Apr 19, 2021 - "One dose of Ivermectin was all it took to get 81-year-old John Swanson off the ventilator. John’s wife Sandra could not believe it. His story is remarkably similar to other cases.... 

"Ralph Lorigo is the lawyer who now has won three court orders forcing New York hospitals to administer Ivermectin to dying patients. Incredibly, these three hospitals and their lawyers fought against the patients, arguing they did not have the right to receive the drug despite a valid prescription written by their doctors. In essence, the argument was that they did not have the right to try a potentially life-saving medication.

"In each of the three cases, the New York State Supreme Court Justices sided with the patient, and in each of the three cases, the patients made near-miraculous recoveries after the Ivermectin was given. In each case, these patients were in the Intensive Care Unit on ventilators, unable to breathe on their own, and universally, after the drug was given, they rapidly improved and were able to breathe on their own.

"Judith Smentkiewicz made national news in January when her family hired Lorigo after the hospital refused a fourth dose of Ivermectin..... Attorney Lorigo and his associate Jon F. Minear reported, 'This lady was on a ventilator, literally on her deathbed, before she was given this drug. As far as we’re concerned, the judge’s order saved this woman’s life.'

"The family of Glenna "Sue" Dickinson happened to see a newspaper article of Judith's remarkable story, and they decided to try Ivermectin as well. Sue Dickinson, 65, contracted COVID-19 on January 7, 2021 ...  and was placed on a ventilator on January 17. The hospital staff advised that her chances of survival were about 40 percent [but] refused to give Sue the Ivermectin. Lorigo and Minear  sought an injunction. State Supreme Court Justice Frank Caruso ordered the hospital to provide the Ivermectin. Dickinson, like Swanson, and Smentkiewicz, came off the ventilator and improved as well.... 

"Ivermectin is widely used by physicians, as there are now 51 studies from around the world, with 50 showing clear benefit and one showing neutral.... Experts worldwide have called for the global and systematic use of Ivermectin to prevent and treat COVID-19. Physicians have recently written about a profit motive by regulatory agencies and Big Pharma to block cheap, safe, and effective treatments like Ivermectin and HCQ [hydroxychloroquine] in favor of ... vaccines and medicines like Remdesivir.... Remdesivir cost[s] $3,100 per dose [while] Ivermectin costs about $2 per dose. It is safer than Tylenol or most vitamins, says Dr. Pierre Kory of the FLCCC Alliance, a group of expert physicians promoting access and information through a nonprofit organization. Dr. Kory and Mr. Lorigo have teamed up to help other hospitalized patients gain access to the life-saving drug....

"The big problem is that information promoting Ivermectin is often censored or silenced as quickly as it is provided. Facebook, Reddit, Change.org, YouTube, and others have recently taken down posts on Ivermectin citing violation of 'community standards.'  Physicians who employ good judgment and scientific studies are considered violators, as well as those who publish factual accounts of Ivermectin-based recovery stories. A recent article exposed the link between large pharmaceutical corporations and government regulatory agencies who have financial entanglements and massive conflicts of interest.

"The disinformation campaign is evident with the publication of articles attempting to cast Ivermectin in a false light, referring to it as an 'animal dewormer' that might be a 'bad idea' for humans to use. In reality, many drugs are common to both humans and animals for treatment, including antibiotics, antifungals, and antiparasitic agents....

"Satoshi Omura won the 2015 Nobel Prize in Medicine for his discoveries leading to the development of Ivermectin. In his praise for Ivermectin and its potential to help in the COVID-19 pandemic, Dr. Omura recently compared Ivermectin to Penicillin, 'one of the greatest discoveries of the twentieth century'.... Ivermectin has already been adopted by 25 percent of the world’s countries to prevent and treat COVID-19.... However, censorship, corruption, hospital lawyers, and disinformation campaigns have continued to stand in the way of its widespread acceptance in the United States. Many have never even heard of it.

"Ivermectin recently won in court in South Africa after a protracted legal battle. Ralph Lorigo has now won his third State Supreme Court Injunction in New York. Will legal strategies also be required in the US to gain FDA approval for Ivermectin to treat COVID-19?"

Read more: https://www.thedesertreview.com/opinion/letters_to_editor/ivermectin-wins-in-court-again-for-human-rights/article_98d26958-a13a-11eb-a698-37c06f632875.html

Wednesday, March 10, 2021

YouTube removes Canadian doctors' Covid video

Concern mounts over censorship of Canadian doctors |  iPolitics - Rachel Emmanuel:

March 9, 2021 - "A video of Canadian doctors listing reasons not to be afraid of COVID-19 was censored within minutes of being posted to YouTube, says a group advocating to end government lockdowns. Liberty Coalition Canada posted the video to YouTube on Monday morning, and 20 minutes later, the video-sharing platform removed the post citing a violation of its policy....

"The move is indicative of the escalating censorship for anyone questioning the government’s approach to COVID-19, contended Independent MP Derek Sloan, a member of the End the Lockdowns National Caucus. 'What we’re seeing is: whatever the prevailing consensus is — if you run counter to that, then you’re silenced,' Sloan told iPolitics on Tuesday. 'But good science is all about consent and discussion, and we seem to be seeing the shutdown of that debate.'

"The video in question was created by The Canada Health Alliance, a group of medical doctors, nurses and other health practitioners with a goal to protect patients’ freedom of choice and autonomy through informed consent. Some professionals in the Canada Health Alliance are also part of the Liberty Coalition initiative Professionals Against Lockdowns. 

"The video, which was posted yesterday, and had been viewed on Rumble nearly 57,000 times at the time of iPolitics’ publication, begins with an introduction from B.C. medical doctor Stephen Malthouse. Malthouse lists a range of reasons not to be afraid of the novel coronavirus, including that: the vast majority of people with COVID-19 have few or no symptoms of being sick; there are less patients in the ICU than in the previous three years; and that yearly deaths since 2001 have remained relatively steady, other than a slight uptick in deaths in 2020, which he attributes to an aging population. He also says COVID deaths in children are so rare the death rate is statistically zero. Meanwhile, the survival rate for those under 50 is greater than 99.9 per cent, or 94.6 per cent for those over 70, before early treatment like Vitamin C or D.... 

"In what Sloan describes as the most controversial part of the video, Malthouse says PCR (polymerase chain reaction) tests are 'practically worthless,' with research now showing that only three per cent of people with a positive PCR actually have COVID-19. This is worth debating because Ottawa is basing most of its decisions off case-counts determined by PRC tests, said Sloan.

Read more: https://ipolitics.ca/2021/03/09/concern-mounts-over-censorship-of-canadian-doctors/

Friday, February 26, 2021

Ivermectin cut COVID deaths 75%, study says

New study suggests ivermectin cuts Covid infections by around 75 per cent | Daily Mail - David Rose: 

February 24, 2021 - "A cheap and safe drug widely used against parasites cuts Covid infections, hospitalisations and deaths by about 75 per cent, a study shows. [A review of] More than 30 trials across the world found that ivermectin causes ‘repeated, consistent, large magnitude improvements in clinical outcomes’ at all stages of the disease. The peer-reviewed study, to be published in the US journal Frontiers of Pharmacology, says the evidence is so strong that the drug – used to treat head lice and scabies – should become a standard therapy everywhere, so hastening the global recovery. 

"Study co-author Professor Paul Marik, director of emergency and pulmonary care at the Eastern Virginia Medical School in the US, said: ‘The data is overwhelming – we are in a pandemic, and this is an incredibly effective way to combat it. If we use ivermectin widely, our societies can open up’....

"An earlier study by Professor Andrew Hill of Liverpool University also concluded that ivermectin cuts death rates by around three-quarters.... He recommended there should be larger trials before it was approved by UK regulators. A new trial of ivermectin as a Covid treatment is due to start shortly at Oxford University.

"Dr Tess Lawrie, director of the Evidence-Based Medicine Consultancy in Bath, convened an online summit of international experts last weekend to discuss the new data. It included evidence that widespread use of ivermectin in parts of India and South America has led to a big reduction in infections and deaths. Yesterday Dr Lawrie submitted a 97-page report to the World Health Organisation, urging it immediately to recommend ivermectin to treat Covid. 

'The drug, taken in tablet form or as drops, is licensed in Britain only as a treatment for parasitic worms, head lice and scabies. It has been used by hundreds of millions of patients over the past 30 years, mainly in developing countries, and at around £50 per patient – less in some countries – is far cheaper than other new Covid treatments, such as the rheumatism drug tocilizumab, which costs £1,000 per patient.

'The UK’s Medicines and Healthcare Regulatory Agency said it was aware of the global study into the use of ivermectin to treat Covid-19 and that its evidence would be reviewed."

Read more: https://www.dailymail.co.uk/news/article-9297449/Drug-used-treat-lice-scabies-drug-cut-Covid-deaths-75-research-suggests.html

Read study: https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Ivermectin-in-the-prophylaxis-and-treatment-of-COVID-19.pdf


Tuesday, February 16, 2021

Vitamin D cut Covid death 60% in Catalonia study

Vitamin D for patients admitted to hospital could cut Covid deaths by 60 per cent | The Telegraph - Sarah Knapton:

February 14, 2021 - "Giving high-dose Vitamin D to coronavirus patients when they are admitted to hospital could cut deaths by 60 per cent – double the benefit of the best current drug, new research suggests. Scientists from the University of Barcelona showed that patients prescribed calcifediol – an intensive dose of Vitamin D usually used for people with chronic kidney failure – had their risk of admission to intensive care dramatically cut and death rates significantly lowered.

"Currently the steroid dexamethasone has shown the greatest impact, reducing deaths by 30 per cent, and is now recommended for seriously ill NHS patients, but the new study suggests calcifediol could be twice as beneficial if given early.

"In the study, 10 per cent of patients admitted to Barcelona's Hospital del Mar with coronavirus died within 30 days. However, while 57 out of 379 (15 per cent) control patients died, just 36 out of 551 (6.5 per cent) of those treated with calcifediol died.

"The researchers found that earlier treatment was better. If given on admission to intensive care, the treatment made no difference. The authors concluded: 'Our results indicate that early calcifediol administration is critical for mortality reduction.... Ultimately these effects are thought to curb the inflammatory cascade that leads to the cytokine and chemokine storm associated with the pathogenesis of acute respiratory distress syndrome (ARDS). Adequate Vitamin D status could also play a role in preventing Covid-19 infection.'

"There has been growing speculation that one of the reasons why black, Asian and minority ethnic (BAME) communities are so disproportionately impacted by coronavirus is endemic low levels of Vitamin D in BAME populations. The vitamin is produced naturally in the body when skin comes into contact with sunshine and is vital for healthy bones, strong muscles and a good immune system. But not as much sunlight can penetrate darker skins, meaning less of the vitamin is produced.... 

"Italy and Spain have both experienced high mortality rates, and scientists found both countries have lower than average Vitamin D levels. This is partly because people in southern Europe, particularly the elderly, avoid strong sun, while their darker skin pigmentation also reduces the body's ability to produce natural Vitamin D. In contrast, the highest average levels of Vitamin D are found in northern Europe, due to high consumption of cod liver oil and Vitamin D supplements, and possibly less sun avoidance.

"Vitamin D has been shown to protect against acute respiratory infections. It also regulates the response of white blood cells, preventing them from releasing too many inflammatory cells which may stop the body overreacting to the virus.

"The study was published as a preprint of The Lancet journal and is yet to be peer reviewed."

Read more: https://www.telegraph.co.uk/news/2021/02/14/giving-hospital-admitted-patients-vitamin-d-could-cut-covid/

Read study here: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318

Tuesday, February 9, 2021

Big Pharma throws ivermectin under the bus

The fight against low-cost and highly effective Ivermectin has begun - Swiss Policy Research:

February 6, 2021 - "Dozens of studies and several meta-studies have already found low-cost ivermectin to be highly effective against covid. In January, even the US NIH [National Institutes of Health] had to change its stance from ‘negative’ to ‘neutral’. Detractors of ivermectin had to act,...

"In their fight against low-cost HCQ [hydroxychloroquine] – which was also found to be effective in the early treatment of high-risk patients, thanks to its anti-inflammatory and anti-thrombotic properties – detractors published a made-up study in the Lancet (the Surgisphere scandal) and ran trials with toxic overdoses in ICU patients (the ‘SOLIDARITY’ and ‘RECOVERY’ trials). But Ivermectin is very difficult to overdose, and unlike HCQ, it works as a prophylaxis against infection and even in ICU patients. Thus, it would be much more difficult to design a deceptive study against ivermectin.

"Finally, a ‘solution’ was found: US pharmaceutical company Merck – one of the manufacturers of patent-free Ivermectin – has just published a statement simply claiming, without evidence, that their (unpublished) 'analysis' had identified 'no scientific basis for a potential therapeutic effect against COVID-19 from pre-clinical studies; no meaningful evidence for clinical activity or clinical efficacy in patients with COVID-19 disease; and a concerning lack of safety data in the majority of studies.'

"An NIH operative quickly retweeted the Merck statement, adding: 'Merck’s statement on ivermectin is the leadership and commitment to quality translational science that we need to see from pharma/biotech.' In reality, Merck’s claim is completely baseless and also ironic: after having safely sold ivermectin for several decades, Merck now suddenly questions its safety....

"Merck recently signed a $356 million deal to supply the US with a much more expensive, newly developed experimental anti-covid drug. Meanwhile, Youtube removed a C-SPAN video of FLCCC President Dr Pierre Kory’s US Senate testimony on ivermectin....

"[A] low-cost and highly effective drug against covid, like Ivermectin, would disrupt not only the multi-billion dollar global vaccine campaign (which does indeed lack long-term safety and efficacy data), but also follow-up ‘lock step’ policies like vaccine passports, smartphone-based global contact monitoring, as well as programs like ID2020 and ‘Known Traveler’ promoted by vaccine investor Bill Gates, the World Economic Forum, and similar groups."

Read more: https://swprs.org/fight-against-ivermectin-begins/

Friday, January 29, 2021

Some countries allow ivermectin use to treat Covid

Use of parasite medication to treat coronavirus patients approved in Slovakia | Slovak Spectator

January 27, 2021 - "Ivermectin, a medication used to treat many types of parasite infestations, can now be used to treat coronavirus patients in hospitals and obtained from pharmacies with a prescription. The Health Ministry approved the therapeutic use of this medication for six months. It will be used with other treatments, its spokesperson Zuzana Eliášová said, as reported by the TASR newswire.

"The medication can be legally imported to Slovakia and given to patients. With such a step, the ministry fulfilled the request of the association of Slovak anaesthetists, the Denník N daily reported. Until now, Ivermectin was officially approved to be used only for animals, which is why people generally buy it abroad."

Read more: https://spectator.sme.sk/c/22583299/use-of-parasite-medication-to-treat-coronavirus-patients-approved-in-slovakia.html


South Africa Allows Use of Parasite Drug in Covid Patients | Bloomberg - Janice Kew:

January 27, 2021 - "South African authorities approved the use of a drug used to control parasites in humans and livestock to treat coronavirus patients. The medicine, known as ivermectin, will be allowed for use on compassionate grounds in a controlled-access program, the head of the South African Health Products Regulatory Authority said Wednesday. Medical practitioners who apply to the regulator to use the drug will be considered on a case-by-case basis, Boitumelo Semete-Makokotlela said.

"Ivermectin has been used for decades to treat livestock infested with parasitic worms, while in humans it’s used as a topical ointment for diseases including skin infections and inflammation. The World Health Organization has suggested the drug has encouraging effects on coronavirus, though like other regulators it’s also said the medication hasn’t been properly evaluated. The drug won’t be limited to patients with known Covid-19 co-morbidities, Semete-Makokotlela said.

"The regulator is already seeing widespread use of ivermectin in an emerging black market, as South Africa grapples with a second wave of coronavirus infections that’s resulted in hospital admissions soaring and a shortage of critical-care beds. Allowing controlled use of the drug will help the regulator monitor its use and enable the body to collect much-needed safety data."

Read more: https://www.bloomberg.com/news/articles/2021-01-27/south-africa-allows-use-of-parasite-drug-to-treat-covid-patients


Zimbabwe OKs use of Ivermectin after officials' deaths | Anadolu Agency - John Cassim:

January 28, 2021 - "Zimbabwe has approved the use and import of the anti-parasite drug Ivermectin to treat COVID-19 patients. 

"'In these difficult times of COVID-19 treatment, we have to be careful to protect patients as well as not to deny them effective treatment regimes,” said a statement by the Health Ministry addressed to the Medicines Control Authority of Zimbabwe (MCAZ). 'It is in this regard, the authority is hereby granted for you to proceed to allow importation and use of these medicines under the supervision and guidance you outlined. Ivermectin can be evaluated for both treatment and prophylaxis,' the ministry said.

"This ministry’s decision comes a few days after the deaths of three cabinet ministers and several top government officials from COVID-19 in a short period of time. Owing to the fact that Ivermectin was not registered for use in Zimbabwe, COVID-19 patients ended up using the Ivermectin product meant for animals....

"Two weeks ago, the medicines control body threatened to arrest anyone found to be administering Ivermectin to humans."

Read more: https://www.aa.com.tr/en/africa/zimbabwe-oks-use-of-ivermectin-after-officials-deaths/2125442

Monday, January 18, 2021

Follow science on vitamin D, experts tell gov'ts

Experts send Vitamin D and Covid-19 open letter to world's governments | NUTRAingredients.com - Nikki Hancocks: 

December 21, 2020 - "In an open letter being sent to world governments today (21st December), 120 health, science and medical experts from the UK, US, and Europe say there is clear scientific evidence that vitamin D reduces Covid-19 infections, hospitalisations, and deaths. In the letter (signed by 120 on Friday 18th but rapidly increasing) scientists are calling for immediate, widespread, increased vitamin D intake to 4,000 International Units (IU) per day (or at least 2,000) for healthy adults.

"This comes just days after the UK government's health bodies SACN [Scientific Advisory Committee on Nutrition] and NICE [National Institute for Health and Care Excellence], denied there is enough evidence to support increasing vitamin D intake for COVID-19 specifically​. ​

"The scientists involved in the open letter say that global patterns and risk factors for the Covid-19 pandemic and Vitamin D deficiency match 'precisely' due to the impact on immune function​. They ... are calling for immediate, widespread, increased vitamin D intakes.... They say new mechanisms specific to SARS-Cov-2 are now very well-understood, with ... ​more than 70 studies showing higher vitamin D levels are associated with lower rates of infection and lower risk of hospitalisation, ICU, or death​, as well as early causal inference studies confirmed by recently published randomised controlled trials​ (RCTs) and quasi-experimental studies.

"The campaign’s main organisers are Dr Karl Pfleger​ (USA) and Dr Gareth Davies​ (UK) - both have backgrounds in Artificial Intelligence and Data Science, as well as Medicine. The letter has a growing list of 120 signatories. More than one hundred are medical doctors or PhDs, or both, and more than 60 are professors. Two British MPs - David Davis and Rupa Huq - have also signed the letter. 

"Martin Hewison, Professor of Molecular Endocrinology at Birmingham University and one of the world’s leading authorities on Vitamin D, has signed the letter after he strongly criticised SACN and NICE, calling their reports 'disappointing'​.  He reacted to the latest NICE report​, stating: 'NICE, SACN and PHE [Public Health England] continue to promote the idea of vitamin D "toxicity", despite no evidence of this in trials where up to 4,000 IU/day vitamin D were used. This obsession has become a major hurdle to better vitamin D health in the UK. Many vitamin D researchers have worked tirelessly over the summer to provide a framework in which vitamin D supplementation could be incorporated into the general strategies being used to defeat COVID-19. NICE, SACN and PHE have rejected this, and their new recommendations provide little or no help at all for the UK public.'

"MP David Davis has been a vocal supporter of vitamin D throughout the pandemic. He says, 'The evidence from several dozen studies show that vitamin D deficiency/insufficiency is implicated in compromising the body’s immune response to respiratory diseases in general and COVID-19 in particular.... In the unlikely event that all this evidence is an artefact, the costs and health risks are minimal. ​In the much more likely event that the multiple sources of observational evidence, and the evidence from the growing number of RCTs, show a real causal role of vitamin D in activating and modulating the immune system, it would be irresponsible not to give vitamin D to all the groups who are at risk from COVID-19. It will save lives, improve population immunity, and help reduce the medical and economic impact whilst we await the universal roll out of vaccines. 

"​Furthermore, if it is to have any material effect the dosage has to be sufficient to correct the existing deficiency, which means up to ten times the UK recommended daily intake.'

"Signatory Dr David S Grimes, a retired gastroenterologist, has campaigned to get vitamin D taken more seriously for years. He says: '[NICE and SACN] have ignored past and current research and instead assert "there is not adequate evidence to support the use of vitamin D". They have denied the NHS the use of calcifediol, a rapid-acting form of vitamin D, in the treatment of Covid-19 pneumonia, despite it being shown in one clinical trial to have 96% efficacy. The UK has had 25,000 COVID-19 deaths since this study was published, yet NICE continues to claim "not enough evidence". They have so much to answer for. They’re a national disgrace.”​

Read more: https://www.nutraingredients.com/Article/2020/12/21/Experts-send-Vitamin-D-and-Covid-19-open-letter-to-world-s-governments